Despite decades of common use for surgeries of all kinds, the precise mechanism through which general anesthesia works on the body remains a mystery. New research investigated the common anesthetic ...

The localized loss of sensation with resultant reduction in pain stimuli is the end result of local anesthesia. This mode of anesthesia is considered to be safer than general anesthesia, because it ...

Anesthetics have been used in surgical procedures for more than 150 years, but the mechanisms by which inhaled anesthesia actually work are poorly understood. Now, researchers have discovered that ...

In a paper recently published in Neuron, researchers from the group of Botond Roska at IOB reveal how different cell types in cortex change their activity during general anesthesia, helping to ...

(A) Schematic diagram of the experimental system that detects calcium release from the endoplasmic reticulum by each ryanodine receptor. (B) Isoflurane selectively activates RyR1 (mean ± standard ...

CAMBRIDGE, MA -- Nitrous oxide, commonly known as "laughing gas," has been used in anesthesiology practice since the 1800s, but the way it works to create altered states is not well understood. In a ...

Mechanical embolectomy performed with general instead of local anesthesia is associated with worse clinical outcomes and poorer survival, according to an article published online March 25, 2014, ahead ...

Since their anesthetic effects were discovered approximately 180 years ago, inhalational anesthetics have been used for general anesthesia in surgical operations. However, the mechanism of their ...

An impressive new study, led by scientists from the Boston Children's Hospital, has developed a novel method to tame one of the world's most potent toxins, tetrodotoxin, commonly found in the ...