The first DNA sequencing was performed by Sanger and co-workers in the 1970s, using a method based on the attenuation of the growing nucleotide chain with dideoxythymidine triphosphate (ddTTP). The ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Due to its high accuracy and fast, simple workflow, capillary electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic variations ...

As questions surrounding paternity fraud and DNA disputes gain prominence, experts maintain that despite the introduction of Next Generation Sequencing [NGS] Capillary Electrophoresis [CE] precision, ...

In 1997, Sanger, Nicklen and Coulson described a method for determining DNA nucleotide sequences. 1 Nearly five decades later, Sanger sequencing remains an entrenched technology for targeted ...

Researchers at the University of Toronto have invented a new method that uses DNA sequencing to measure metabolites. This enables rapid and precise analysis of biological compounds, such as sugars, ...